|
KMID : 0613820080180121739
|
|
Journal of Life Science
2008 Volume.18 No. 12 p.1739 ~ p.1744
|
|
|
The Effects of Short-term Exercise and Capsaicin Supplementation on Serum Lipids, Antioxidants and Akt Contents in STZ-induced Diabetic Rats
|
|
Seo Dae-Yun
Ko Jeong-Rim
Baek Yeong-Ho
|
|
|
Abstract
|
|
|
|
The purpose of this study was investigate the effects of short-term exercise and capsaicin supplementation on serum lipids, antioxidants and Akt contents in diabetic rats whose symptom was induced through the use of 50 ㎎/㎏ streptozotocin, 31 white rats were experimented. Rats in one exercise group and another exercise-capsaicin supplementation group exercised on a treadmill maintained by a 15-min run at 0° inclination five times for a week during two weeks one week after the diabetes was induced. 10 ㎎ of capsaicin per kilogram of weight was orally administered to rats in the capsaicin supplementation group after the diabetes was induced. The serum lipids were analyzed through the use of blood obtained from the incision of the abdomen, and antioxidants and Akt contents were analyzed through the use of livers to reach following conclusions. As for the serum lipids, TG significantly decreased in group DCE and HDL-C was higher than in other groups. ROS significantly decreased in all groups except for group D. CAT significantly increased in group DC, SOD was significantly high in groups DE and GSH was significantly high in all groups except for D. Akt contents significantly increased in group DC and p-Akt in group DE. As a result of this study, it has been found that short-term exercise and the capsaicin supplementation had a significantly effect on the serum lipids, antioxidants and Akt contents.
|
|
|
KEYWORD
|
|
|
Capsaicin, SOD, CAT, GSH, Akt
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|